Role of the human chymase (CMA1) in the conversion of big-endothelin-1 to endothelin-1 (1-31)
Abstract : The chymase-dependant pathway responsible for converting Big ET-1 to ET-1 was established in vitro. It has only been recently, in 2009, that our group demonstrated that the conversion of Big ET-1 to ET-1 (1-31) can occur in vivo in mice (Simard et al., 2009), knowing that ET-1 (1-31) is...
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Language: | English |
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Université de Sherbrooke
2016
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Online Access: | http://hdl.handle.net/11143/9806 |