The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells

EOC (epithelial ovarian cancer) is a leading cause of death from gynecological cancers. The majority of the patients with EOC are diagnosed at a late stage. The survival of these patients is limited due to recurrence of chemotherapy resistant disease. Therefore, the development of novel therapeutic...

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Bibliographic Details
Main Author: Goncharenko Khaider, Nadzeya
Other Authors: Piché, Alain
Language:English
Published: Université de Sherbrooke 2011
Subjects:
Bid
Online Access:http://savoirs.usherbrooke.ca/handle/11143/4083