Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model

Aim: Design nanostructured lipid carriers (NLC) to facilitate drug delivery to tuberculosis-infected areas, exploiting macrophage mannose receptors and assess their uptake in a 3D human lung model. Materials & methods: NLCs and mannosylated-NLCs were synthetized and characterized. Their uptake a...

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Bibliographic Details
Main Author: Marina Barroso Pereira Pinheiro
Other Authors: Faculdade de Medicina
Format: Others
Language:Portuguese
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10216/128679