Effect of tetrahydrocannabinol on COMT activity in mice prefrontal cortex

Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and its effects are modulated by dopaminergic neurotransmission. Dopamine availability in prefrontal cortex is mostly controlled by catechol-o-methyltransferase (COMT) and it has been suggested that THC induced psychosi...

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Bibliographic Details
Main Author: Ana Catarina Relvas do Novo
Other Authors: Faculdade de Medicina
Format: Others
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10216/119848