Myeloid AMPK in Atherosclerosis: Therapeutic Potential and Associated Mechanisms

Atherosclerosis propagates when innate immune cells, myeloid-derived macrophages, undergo unregulated uptake of cholesterol-rich modified low-density lipoproteins (LDL). Excess storage and retention of this cholesterol leads to development of lipid-laden macrophage foam cells, that accumulate within...

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Bibliographic Details
Main Author: LeBlond, Nicholas
Other Authors: Fullerton, Morgan
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2020
Subjects:
Online Access:http://hdl.handle.net/10393/41211
http://dx.doi.org/10.20381/ruor-25435