Myeloid AMPK in Atherosclerosis: Therapeutic Potential and Associated Mechanisms
Atherosclerosis propagates when innate immune cells, myeloid-derived macrophages, undergo unregulated uptake of cholesterol-rich modified low-density lipoproteins (LDL). Excess storage and retention of this cholesterol leads to development of lipid-laden macrophage foam cells, that accumulate within...
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Format: | Others |
Language: | en |
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Université d'Ottawa / University of Ottawa
2020
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Online Access: | http://hdl.handle.net/10393/41211 http://dx.doi.org/10.20381/ruor-25435 |