Critical Examination of Selected Aspects of the ToxTracker In Vitro Genotoxicity Assay: Evaluation of S9 Metabolic Activation Protocols and Quantitative Interpretation of Dose-response Data
Genotoxic effects such as mutations and chromosome abnormalities can augment the risk of adverse health effects such as cancer and heritable genetic diseases; chemicals in commerce must be screened for genotoxic activity. To this end, Toxys B.V. developed the in vitro ToxTracker® assay, which detect...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2020
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| Online Access: | http://hdl.handle.net/10393/41152 http://dx.doi.org/10.20381/ruor-25376 |