MiR-1908 Is a Cholesterol Responsive MicroRNA Implicated In Cholesterol Regulation

Leveraging miRNA-Seq data and the 1000 Genomes imputed genotypes, we identified rs174561-C as a strong miRQTL for circulating miRNA-1908-5p (P=4.8x10-31) which has an inverse relationship with circulating LDL-C, fasting glucose and A1c. Here I investigated the molecular mechanism(s) linking miR1908-...

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Bibliographic Details
Main Author: Beehler, Kaitlyn
Other Authors: McPherson, Phyllis
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2020
Subjects:
Online Access:http://hdl.handle.net/10393/40422
http://dx.doi.org/10.20381/ruor-24655