Bio-Engineering Vaccinia Viruses for Increased Oncolytic Potential

Vaccinia virus has a large and still incompletely understood genome although several strains of this virus are already in clinical development. For the most part, clinical candidates have been attenuated from their wild type vaccine strains through deletion of metabolic genes like the viral thymidin...

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Bibliographic Details
Main Author: Pelin, Adrian
Other Authors: Bell, John
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2019
Subjects:
Online Access:http://hdl.handle.net/10393/39909
http://dx.doi.org/10.20381/ruor-24148