Development and Validation of a Structure-Based Computational Method for the Prediction of Protein Specificity Profiles

Post-translational modification (PTM) of proteins by enzymes such as methyltransferases, kinases and deacetylases play a crucial role in the regulation of many metabolic pathways. Determining the substrate scope of these enzymes is essential when studying their biological role. However, the combinat...

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Bibliographic Details
Main Author: Gagnon, Olivier
Other Authors: Chica, Roberto
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2019
Subjects:
Web
Online Access:http://hdl.handle.net/10393/39643
http://dx.doi.org/10.20381/ruor-23886