Administration of Human Endothelial Colony Forming Cell-Derived Exosomes and miR-486-5p Protects Against Ischemia/Reperfusion Acute Kidney Injury

Background: Acute kidney injury (AKI) is a highly prevalent clinical disorder with significant mortality and no current treatment. The Burns Lab has previously shown that endothelial colony forming cells (ECFCs) release exosomes highly enriched in pro-survival micro-RNA-486-5p. In our mouse model of...

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Bibliographic Details
Main Author: Spence, Matthew
Other Authors: Burns, Kevin D.
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2019
Subjects:
Online Access:http://hdl.handle.net/10393/39341
http://dx.doi.org/10.20381/ruor-23588