Role of Macrophage Subsets in CD8+ T Cell Dysfunction in Chronic HCV Infection
Chronic HCV infection causes generalized CD8+T cell impairment, not limited to HCV-specific CD8+ T cells. Infiltrating monocyte-derived macrophages contribute to a micro- environment that could impact CD8+T cells trafficking through the liver. Macrophages can differentiate into pro-inflammatory (M1)...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2018
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| Online Access: | http://hdl.handle.net/10393/38227 http://dx.doi.org/10.20381/ruor-22481 |