Early-Life Exposure to the Antidepressant Fluoxetine Induces a Male-Specific Transgenerational Disruption of the Stress Axis and Exploratory Behavior in Adult Zebrafish, Danio rerio

Selective serotonin (5-HT) reuptake inhibitors (SSRIs) particularly fluoxetine (FLX, Prozac®), are often the first-line of pharmacological treatment for affective disorders in pregnant women. Given that SSRIs readily cross the placenta, a fetus from a SSRI-treated pregnant woman is potentially at ri...

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Bibliographic Details
Main Author: Vera Chang, Marilyn Nohely
Other Authors: Trudeau, Vance
Format: Others
Language:en
Published: Université d'Ottawa / University of Ottawa 2018
Subjects:
Online Access:http://hdl.handle.net/10393/38028
http://dx.doi.org/10.20381/ruor-22283