Small Molecule Potentiators of Oncolytic Virus Therapy Suppress the Innate Antiviral Response
Oncolytic Viruses (OVs) are often attenuated to increase their safety profile, however this can lead to reduced efficacy in heterogeneous malignancies and result in resistance to OV therapy. Our group utilizes small molecule enhancers of OV therapy termed viral sensitizers. These small molecules hav...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2018
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| Online Access: | http://hdl.handle.net/10393/37115 http://dx.doi.org/10.20381/ruor-21387 |