Characterization of the Molecular Mechanism by which SMN Regulates mRNA Translation
Despite our understanding of the role of the survival motor neuron protein (SMN) in cytoplasmic small ribonucleoproteins (snRNP) assembly, it is unclear how loss of this protein causes motor neuron degeneration in Spinal Muscular Atrophy (SMA). It could be explained by defects in functions that are...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2017
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Online Access: | http://hdl.handle.net/10393/37057 http://dx.doi.org/10.20381/ruor-21329 |