Motor Deficits in an Alpha-Synuclein Mouse Model of Parkinson's Disease are not Exacerbated by Gba1 Mutation
Parkinson’s disease is a movement disorder characterized by nigrostriatal dopamine pathway degeneration and neuronal α-synuclein accumulation. Pathogenesis is associated with mutations in α-synuclein and Gba1 encoding alleles. Animal models created to date do not recapitulate the spectrum of clinica...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2017
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| Online Access: | http://hdl.handle.net/10393/35689 http://dx.doi.org/10.20381/ruor-646 |