Translationally Controlled Tumour Protein as a Novel Therapeutic Target in Pulmonary Arterial Hypertension

Background: Pulmonary arterial hypertension (PAH) is a multifaceted disease characterized by elevated pulmonary arterial pressure, right ventricular hypertrophy, and a poor prognosis. Pathological hallmarks of PAH include pulmonary vascular remodelling, pre-capillary arterial obliteration, and plexi...

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Bibliographic Details
Main Author: Foster, William Swinburne
Other Authors: Stewart, Duncan
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/35006
http://dx.doi.org/10.20381/ruor-5062