Characterization and Elucidation of Genomic Modifiers of DJ-1 and LRRK2 Animal Models of Parkinson’s Disease

Parkinson’s disease (PD) is a common neurodegenerative disorder symptomatically characterized by motor dysfunction caused by the selective loss of nigral dopamine neurons within midbrain. The pathogenesis of PD remains unclear. Although, originally thought to be sporadic, about ten percent of PD is...

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Bibliographic Details
Main Author: Marcogliese, Paul C.
Other Authors: Park, David S.
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/34860
http://dx.doi.org/10.20381/ruor-893