Release of Soluble Interleukin-7 α Receptor (CD127) from CD8+ T-Cells and Human Thymocytes

ABSTRACT Background Interleukin-7 (IL-7) is a cytokine crucial for T-cell development and homeostasis. IL-7 is thought to be a limited resource, and its interaction with the IL-7 receptor (IL-7R) has effects on increasing cell survival, proliferation and cytolytic function. Considering the roles...

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Bibliographic Details
Main Author: Sanchez Vidales, Maria Del Mar
Other Authors: Angel, Jonathan B.
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/34631
http://dx.doi.org/10.20381/ruor-5792