Effects of Chronic Insulin and High Glucose on Insulin-Stimulated Responses in Human Preadipocytes

The preadipocyte is crucial for healthy adipose tissue (AT) remodeling, and insulin resistance in these cells may contribute to AT dysfunction. Chronic exposure to insulin and high glucose induces insulin resistance in the 3T3-L1 mouse adipocyte cell line in vitro, however, whether this occurs in hu...

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Bibliographic Details
Main Author: El Bilali, Jason
Other Authors: Sorisky, Alexander
Language:en
Published: Université d'Ottawa / University of Ottawa 2016
Subjects:
Online Access:http://hdl.handle.net/10393/34109
http://dx.doi.org/10.20381/ruor-5962