Investigation of Cis and Trans-acting Transcriptional Regulatory Factors and Signaling Pathways of Parkin

Parkin gene is associated with the development of autosomal recessive juvenile parkinsonism (Kitada et al., 1998) which is a common form of familial Parkinson’s disease (Klein and Schlossmacher, 2006). Since Parkin has multiple cell protective effects, increasing the expression level of Parkin in th...

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Bibliographic Details
Main Author: Ao, Hei Sio
Other Authors: Schlossmacher, Michael
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/33368
http://dx.doi.org/10.20381/ruor-4029