Functional Regulation at the 9p21.3 Genetic Risk Locus in Coronary Artery Disease (CAD)

The first genetic CAD risk locus to be identified by genome-wide association studies, single nucleotide polymorphisms (SNPs) at 9p21.3 predispose to increased risk of CAD. By bioinformatics scan analysis of the 9p21.3 locus; we interrogated the 59 linked SNPs over the 53,202bp to identify putative t...

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Bibliographic Details
Main Author: Antoine, Darlène
Other Authors: Stewart, Alexandre
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/33148
http://dx.doi.org/10.20381/ruor-4083