Effects of Pharmacological Manipulation of the Serotonergic/Cholinergic Systems on Sleep Structure in Two 5-HT1A Genotypes: Implications for a Model of Depression

Effects of Pharmacological Manipulation of the Serotonergic/Cholinergic Systems on Sleep Structure in Two 5-HT1A Genotypes: Implications for a Model of Depression

The serotonergic and cholinergic systems are jointly involved in regulating sleep but this balance is theorized to be disturbed in depressed individuals (Janowsky 1972, Jouvet 1972). One potential cause of disturbed neurotransmission is genetic predisposition. The G(-1019) allele of the 5-HT1A recep...

Full description

Bibliographic Details
Main Author: Biard, Kathleen
Other Authors: De Koninck, Joseph
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Sleep
Depression
Sleep structure
REM
serotonin
acetylcholine
buspirone
galantamine
neurotransmission
5-HT1A receptor
genetic risk factors
Online Access:http://hdl.handle.net/10393/33005
http://dx.doi.org/10.20381/ruor-4108

Internet

http://hdl.handle.net/10393/33005
http://dx.doi.org/10.20381/ruor-4108

Similar Items