The Role of Ldb1 in ErbB2/Neu-induced Mammary Tumorigenesis

The ste-20 like kinase (SLK) is a serine/threonine kinase activated downstream of Neu signaling and functions to mediate efficient migration and invasion of breast cancer cells. Previously, the LIM domain binding protein 1 (Ldb1) has been identified as a negative regulator of SLK kinase activity in...

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Bibliographic Details
Main Author: Ahmed, Sarra
Other Authors: Sabourin, Luc
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Online Access:http://hdl.handle.net/10393/32864
http://dx.doi.org/10.20381/ruor-2836