Structural and Biochemical Dissection of the KMT2 Core Complex
Histone H3 lysine 4 (H3K4) methylation is an evolutionarily conserved mark commonly associated with transcription activation in eukaryotes. In mammals, this post-translational modification is deposited by the KMT2 family of H3K4 methyltransferases. Biochemical studies have shown that the enzymatic a...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2015
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Online Access: | http://hdl.handle.net/10393/32479 http://dx.doi.org/10.20381/ruor-4754 |