The Characterization of the Novel Chloroquine Derivative VR23 for its Anticancer Properties

Since Bortezomib®, a proteasome inhibitor, was approved by US FDA for the treatment of multiple myeloma in 2003, proteasome is recognized as one of the most promising targets for cancer therapeutics. The proteasomes play a critical role in regulating the level of cellular proteins and recycling dama...

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Bibliographic Details
Main Author: Pundir, Sheetal
Other Authors: Lee, Hoyun
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Subjects:
Online Access:http://hdl.handle.net/10393/32405
http://dx.doi.org/10.20381/ruor-4368