Caspase 3 Cleavage of Pax7 Inhibits Self-Renewal of Satellite Cells

Compensatory growth and regeneration of skeletal muscle is dependent on the resident stem cell population, termed satellite cells. Self-renewal and maintenance of the satellite cell niche is coordinated by the transcription factor Pax7, yet continued expression of this protein inhibits the myoblast...

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Bibliographic Details
Main Author: Dick, Sarah
Other Authors: Megeney, Lynn
Language:en
Published: Université d'Ottawa / University of Ottawa 2015
Online Access:http://hdl.handle.net/10393/32233
http://dx.doi.org/10.20381/ruor-4999