Systems Regulating and Inducing Dopaminergic Cell Death in Parkinson’s Disease: an Analysis of Signalling Associated with Parkinson's Disease Models
Parkinson’s disease (PD) is characterized by the progressive loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNc). Mechanisms regulating this neurodegeneration, however, are unclear. Evidence from PD pathology and models of PD, indicate mitochondrial disfunction triggers several...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2015
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Online Access: | http://hdl.handle.net/10393/32053 http://dx.doi.org/10.20381/ruor-2755 |