The Copper(I)-catalyzed Azide–Alkyne Cycloaddition: A Modular Approach to Synthesis and Single-Molecule Spectroscopy Investigation into Heterogeneous Catalysis
Click chemistry is a molecular synthesis strategy based on reliable, highly selective reactions with thermodynamic driving forces typically in excess of 20 kcal mol-1. The 1,3-dipolar cycloaddition of azides and alkynes developed by Rolf Huisgen saw dramatic rate acceleration using Cu(I) as a cataly...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2014
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Online Access: | http://hdl.handle.net/10393/31882 http://dx.doi.org/10.20381/ruor-6781 |