Functional Genetic Analysis Reveals Intricate Roles of Conserved X-box Elements in Yeast Transcriptional Regulation

Functional Genetic Analysis Reveals Intricate Roles of Conserved X-box Elements in Yeast Transcriptional Regulation

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Understanding the functional impact of physical interactions between proteins and DNA on gene expression is important for developing approaches to correct disease-associated gene dysregulation. I conducted a systematic, functional genetic analysis of protein-DNA interactions in the promoter region o...

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Bibliographic Details
Main Author: Voll, Sarah
Other Authors: Kaern, Mads
Language:en
Published: Université d'Ottawa / University of Ottawa 2013
Subjects:
functional genetic analysis
transcription factor (TF)
cis-regulatory element (CRE)
binary interaction
higher order interaction
multiple linear regression
additive
multiplicative
synthetic genetic array (SGA)
green fluorescent protein (GFP)
ribonucleotide reductase (RNR)
yeast
X-box
transcriptional regulation
RNR3
Online Access:http://hdl.handle.net/10393/30168
http://dx.doi.org/10.20381/ruor-3364

Internet

http://hdl.handle.net/10393/30168
http://dx.doi.org/10.20381/ruor-3364

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