Proteomic Analysis Identifies Translationally Controlled Tumor Protein as a Potential Novel Mediator of Occlusive Vascular Remodeling in Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a lethal disease characterized by excessive proliferation of pulmonary vascular cells, such as endothelial cells (ECs). Hereditary (H) PAH is mainly caused by ―loss-of-function‖ mutations in the gene coding for the bone morphogenetic protein type II receptor...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2013
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| Online Access: | http://hdl.handle.net/10393/24243 http://dx.doi.org/10.20381/ruor-3044 |