The Role of Neutral Sphingolipids in the Pathogenesis of Parkinson Disease and Dementia with Lewy Bodies

The molecular mechanisms underlying the association between mutations in GBA1 and risk of developing the ‘synucleinopathy’ disorders Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) remain elusive. To better understand the precise molecular cascade that connects GBA1 mutations with α-syn...

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Bibliographic Details
Main Author: Singh, Priyanka
Other Authors: Schlossmacher, Michael
Language:en
Published: Université d'Ottawa / University of Ottawa 2013
Subjects:
Online Access:http://hdl.handle.net/10393/24029
http://dx.doi.org/10.20381/ruor-2936