Identification and Characterization of an Arginine-methylated Survival of Motor Neuron (SMN) Interactor in Spinal Muscular Atrophy (SMA)

Spinal Muscular Atrophy (SMA) is a neuronal degenerative disease caused by the mutation or loss of the Survival Motor Neuron (SMN) gene. The cause for the specific motor neuron susceptibility in SMA has not been identified. The high axonal transport/localization demand on motor neurons may be one po...

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Bibliographic Details
Main Author: Tadesse, Helina
Other Authors: Côté, Jocelyn
Language:en
Published: Université d'Ottawa / University of Ottawa 2012
Subjects:
Online Access:http://hdl.handle.net/10393/23588
http://dx.doi.org/10.20381/ruor-6263