Genetic Ablation of the Platelet Activating Factor Receptor Does Not Impair Learning and Memory in Wild-Type Mice or Alter Amyloid Plaque Number in a Transgenic Model of Alzheimer’s Disease
We have recently established that aberrant alkylacylglycerophosphocholine metabolism results in the increased tissue concentration of platelet activating factors (PAFs) in the temporal cortex of Alzheimer Disease (AD) patients and in TgCRND8 mice over-expressing mutant human amyloid precursor protei...
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| Format: | Others |
| Language: | en |
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Université d'Ottawa / University of Ottawa
2012
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| Online Access: | http://hdl.handle.net/10393/20627 http://dx.doi.org/10.20381/ruor-5394 |