The Role of the Defective Nav1.4 Channels in the Mechanism of Hyperkalemic Periodic Paralysis
Hyperkalemic periodic paralysis (HyperKPP) is an autosomal dominant human skeletal muscle channelopathy that causes periods of myotonic discharge and periodic paralysis due to defective Nav1.4 sodium channels. Patients are asymptomatic at birth, attacks become short and frequent during childhood, an...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2012
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| Online Access: | http://hdl.handle.net/10393/20550 http://dx.doi.org/10.20381/ruor-5162 |