SLK-mediated Phosphorylation of Paxillin Is Required for Focal Adhesion Turnover and Cell Migration
The precise mechanism regulating focal adhesion disassembly has yet to be elucidated. Recently, we have implicated the Ste20-like kinase SLK in mediating efficient focal adhesion turnover and cell migration in a Rac-1 and FAK-dependent manner. Although an indirect association of this kinase with the...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2011
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| Online Access: | http://hdl.handle.net/10393/20483 http://dx.doi.org/10.20381/ruor-5093 |