Signalling Towards IRES
XIAP and Bcl-xL are critical anti-apoptotic molecules that directly inhibit caspases and block mitochondrial membrane permeabilization, respectively. In addition to preventing apoptosis, both XIAP and Bcl-xL can be generated by cap-independent translation via the utilization of an IRES in the 5'...
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| Language: | en |
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Université d'Ottawa / University of Ottawa
2011
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| Online Access: | http://hdl.handle.net/10393/19946 http://dx.doi.org/10.20381/ruor-4562 |