The Role of Thromboxane A2 Receptors in Diabetic Kidney Disease

Thromboxane receptor (TPr) activity is elevated in diabetes and contributes to complications of diabetic kidney disease (DKD). TPr blockade appears to have therapeutic potential. Several rodent models of DKD show attenuation of renal damage and proteinuria upon administration of the TPr antagonist,...

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Bibliographic Details
Main Author: Shaji, Roya
Other Authors: Kennedy, Christopher
Language:en
Published: Université d'Ottawa / University of Ottawa 2011
Subjects:
Online Access:http://hdl.handle.net/10393/19759
http://dx.doi.org/10.20381/ruor-4416