The Role of Thromboxane A2 Receptors in Diabetic Kidney Disease
Thromboxane receptor (TPr) activity is elevated in diabetes and contributes to complications of diabetic kidney disease (DKD). TPr blockade appears to have therapeutic potential. Several rodent models of DKD show attenuation of renal damage and proteinuria upon administration of the TPr antagonist,...
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Language: | en |
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Université d'Ottawa / University of Ottawa
2011
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Online Access: | http://hdl.handle.net/10393/19759 http://dx.doi.org/10.20381/ruor-4416 |