Historical and Functional Insights into Toll-like Receptor 4 Activation by Lipopolysaccharide and Calgranulins

Toll-like receptor 4 (TLR4) is an important vertebrate innate immune receptor. TLR4 recognizes both endogenous and exogenous danger signals to trigger an NF-kB dependent inflammatory response. While exogenous danger signal recognition is an essential part of pathogen response by the innate immune sy...

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Bibliographic Details
Main Author: Loes, Andrea
Other Authors: Harms, Michael
Language:en_US
Published: University of Oregon 2019
Subjects:
Online Access:http://hdl.handle.net/1794/24528