Historical and Functional Insights into Toll-like Receptor 4 Activation by Lipopolysaccharide and Calgranulins
Toll-like receptor 4 (TLR4) is an important vertebrate innate immune receptor. TLR4 recognizes both endogenous and exogenous danger signals to trigger an NF-kB dependent inflammatory response. While exogenous danger signal recognition is an essential part of pathogen response by the innate immune sy...
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Language: | en_US |
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University of Oregon
2019
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Online Access: | http://hdl.handle.net/1794/24528 |