Molecular Mechanisms for the Evolution of DNA Specificity in a Transcription Factor Family
Transcription factors (TFs) bind to specific DNA sequences near target genes to precisely coordinate their regulation. Despite the central role of transcription factors in development and homeostasis, the mechanisms by which TFs have evolved to bind and regulate distinct DNA sequences are poorly und...
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Language: | en_US |
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University of Oregon
2015
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Online Access: | http://hdl.handle.net/1794/18723 |