Auto-Regulation of the MBNL1 Pre-mRNA
xiv, 59 p. : ill. (some col.) === Muscleblind-like 1 (MBNL1) is a splicing factor whose improper cellular localization is a central component of myotonic dystrophy (DM). In DM, the lack of properly localized MBNL1 leads to mis-splicing of many pre-mRNAs. The mechanism by which MBNL1 regulates it pre...
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Language: | en_US |
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University of Oregon
2011
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Online Access: | http://hdl.handle.net/1794/11533 |