Development of von Willebrand Factor Zebrafish Mutant Using CRISPR/Cas9 Mediated Genome Editing

von Willebrand factor (VWF) protein acts in the intrinsic coagulation pathway by stabilizing FVIII from proteolytic clearance and at the site of injury, by promoting the adhesion and aggregation of platelets to the exposed subendothelial wall. von Willebrand disease (VWD) results from quantitative...

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Bibliographic Details
Main Author: Toffessi Tcheuyap, Vanina
Other Authors: Jagadeeswaran, Pudur
Format: Others
Language:English
Published: University of North Texas 2017
Subjects:
Online Access:https://digital.library.unt.edu/ark:/67531/metadc984227/