Toxicological Evaluation for the Ocular Administration of Tolrestat: An Aldose Reductase Inhibitor for the Treatment of Diabetes

Aldose reductase inhibitors (ARI's) have been shown to attenuate or prevent several complications of diabetes in animals. Tolrestat is a potent and unique ARI from Ayerst Laboratories, New York, NY. The efficacy and toxicology of tolrestat via topical ocular administration was examined. Tolrest...

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Bibliographic Details
Main Author: Carney, Gerald R.
Other Authors: Wimbish, Gary Harold
Format: Others
Language:English
Published: North Texas State University 1987
Subjects:
Online Access:https://digital.library.unt.edu/ark:/67531/metadc935757/