Impact of a Genetically Engineered Probiotic Therapy and IGF-1 Genomics in the PAHenu2 Mouse Model of PKU
Absence of functional phenylalanine hydroxylase results in phenylketonuria (PKU). Viable treatments remain few, expensive and secondary conditions such as osteopenia occur in most PKU patients. Objective 1: Given the recently described roles of gut microbes to aid host digestion, an orally administ...
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Format: | Others |
Language: | English |
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University of North Texas
2015
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Online Access: | https://digital.library.unt.edu/ark:/67531/metadc822730/ |