Synthesis and SAR study of Meperidine Analogues as Selective Serotonin Reuptake Inhibitors (SSRIs)
Meperidine has been shown to have potent binding affinity for serotonin transporters (SERT) (Ki = 41 nM) and be an inhibitor of serotonin reuptake. Based upon these pharmacological results meperidine has been identified as a lead compound for the development of a novel class of serotonin-selectiv...
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| Format: | Others |
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ScholarWorks@UNO
2010
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| Online Access: | http://scholarworks.uno.edu/td/1111 http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=2092&context=td |