Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology

Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology

Show other versions (1)

This study concerns a new antiretroviral drug named CRS 74. This molecule has a limited bioavailability because of its low aqueous solubility, poor water wettability and low dissolution rate. In an attempt to improve these properties, CRS 74 was recrystallized by using a Liquid Anti-Solvent (LAS) cr...

Full description

Bibliographic Details
Main Author:	Paiva Lacerda, Suênia de
Format:	Others
Published:	2013
Online Access:	http://oatao.univ-toulouse.fr/9301/1/de_paiva_lacerda.pdf

Similar Items

Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology
by: Paiva Lacerda, Suênia de
Published: (2013)

Role of Solvents in Improvement of Dissolution Rate of Drugs: Crystal Habit and Crystal Agglomeration
by: Maryam Maghsoodi
Published: (2015-03-01)

Production of Nano-sized Curcumin and Enhancement of Its Dissolution Rate by Using Supercritical Anti-solvent Crystallization
by: Pai-Chang Wu, et al.
Published: (2014)

Improvement of the Micromeritic Characteristics and the Dissolution Rate of Drug Crystals by the Spherical Crystallization Technique
by: Chih Cheng Lin, et al.
Published: (2003)

An impact of nanocrystals on dissolution rate of Lercanidipine: Supersaturation and crystallization by addition of solvent to antisolvent
by: Dolly Tulsibhai Gadhiya, et al.
Published: (2021-06-01)

Enhancing Betulinic Acid Dissolution Rate and Improving Antitumor Activity via Nanosuspension Constructed by Anti-Solvent Technique
by: Li S, et al.
Published: (2020-01-01)

Enhance dissolution rate and solubility of solid drugs through pharmaceutical deep eutectic solvents
by: Idrees Bakr Qader
Published: (2021-06-01)

Multicomponent Crystallization of Ketoprofen-nicotinamide for Improving the Solubility and Dissolution Rate
by: Yudi Wicaksono, et al.
Published: (2018-12-01)

The Study Of Drug Dissolution Rate
by: 陳鈿鍇
Published: (2000)

Solubility and Dissolution Rate Determination of Different Antiretroviral Drugs in Different pH Media Using UV Visible Spectrophotometer
by: K. Prakash, et al.
Published: (2008-01-01)

Anti-Solvent Crystallization
by: Zai-Qun Yu, et al.
Published: (2020-08-01)

Lowering lattice forces in drug substance crystals to improve dissolution and solubility
by: Widmer, Toni
Published: (2015)

Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates.
by: Blagden, Nicholas, et al.
Published: (2011)

Dissolution rate enhancement of poorly water-soluble drugs using lyophilisation technology
by: Mansour, Heba Fathy
Published: (2010)

Dissolution rate of poorly soluble drugs : Potential influence on dissolution rate using calcium sulfate as carrier in drug formulations
by: Eriksson, Johnny
Published: (2012)

Improved Solubility and Dissolution Rates in Novel Multicomponent Crystals of Piperine with Succinic Acid
by: Erizal Zaini, et al.
Published: (2020-04-01)

Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability
by: Prakash Khadka, et al.
Published: (2014-12-01)

Probing Interactions in Combined Hydroxide Base Solvents for Improving Dissolution of Cellulose
by: Beatrice Swensson, et al.
Published: (2020-06-01)

Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals
by: Xufei Bian, et al.
Published: (2020-03-01)

Liquisolid pellets: A pharmaceutical technology strategy to improve the dissolution rate of ritonavir
by: Brenda De Espíndola, et al.
Published: (2019-07-01)

A New Co-Crystal of Synthetic Drug Rosiglitazone with Natural Medicine Berberine: Preparation, Crystal Structures, and Dissolution
by: Xiaoshu Guan, et al.
Published: (2020-09-01)

Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug
by: Mayank Patel, et al.
Published: (2019-01-01)

Improvement of the Dissolution Rate of a Poorly Water-Soluble Drug by Co-grinding Technique
by: Tung Sheng Shieh, et al.
Published: (2004)

Impact of Crystal Habit on the Dissolution Rate and In Vivo Pharmacokinetics of Sorafenib Tosylate
by: Chi Uyen Phan, et al.
Published: (2021-06-01)

Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan
by: Naveen Chella, et al.
Published: (2012-10-01)

Preparation of Solid Dispersions of Simvastatin and Soluplus Using a Single-Step Organic Solvent-Free Supercritical Fluid Process for the Drug Solubility and Dissolution Rate Enhancement
by: Uttom Nandi, et al.
Published: (2021-08-01)

Optimization of L-serine crystallization using methanol as an anti-solvent
by: Kennedy, Victoria Angela
Published: (2006)

Dissolution Behavior of Cellulose in IL + DMSO Solvent: Effect of Alkyl Length in Imidazolium Cation on Cellulose Dissolution
by: Airong Xu, et al.
Published: (2015-01-01)

Lignocellulosic Biomass Dissolution and Fractioning Using Ionic Liquids as a Solvent
by: B. Liebmann, et al.
Published: (2012-09-01)

Investigation and Optimization of a Solvent / Anti-Solvent Crystallization Process for the Production of Inhalation Particles
by: Agrawal, Swati
Published: (2010)

Crystallization and dissolution of electrolyte salts
by: Βαβουράκη, Αικατερίνη
Published: (2010)

Enhancing Dissolution Rate and Antibacterial Efficiency of Azithromycin through Drug-Drug Cocrystals with Paracetamol
by: Noor Ul Islam, et al.
Published: (2021-08-01)

A Hybrid Framework for Simultaneous Process and Solvent Optimization of Continuous Anti-Solvent Crystallization with Distillation for Solvent Recycling
by: Jiayuan Wang, et al.
Published: (2020-01-01)

Improved dissolution of ibuprofen after crystallization from polymeric solution: Correlation with crystal parameter
by: Sahoo Narayan Rudra, et al.
Published: (2021-01-01)

The dissolution rate of chrysotile
by: Hume, Lily Ann
Published: (2014)

Effect of crystal anisotropy and crystal defects on dissolution
by: Burt, Helen Mary
Published: (2010)

Crystal properties of drugs and solvent-deposition : Studies on spironolactone
by: Al-Sarraj, F. A.
Published: (1983)

Investigate the dissolution rate and mechanism of the quinolone drug in different pH
by: Chun-Ta Hou, et al.
Published: (2003)

Crystal Structures, Thermal Analysis, and Dissolution Behavior of New Solid Forms of the Antiviral Drug Arbidol with Dicarboxylic Acids
by: Alex N. Manin, et al.
Published: (2015-12-01)

Preparation and evaluation of azithromycin binary solid dispersions using various polyethylene glycols for the improvement of the drug solubility and dissolution rate
by: Ehsan Adeli