Improvement of dissolution rate of a new antiretroviral drug using an anti-solvent crystallization technology
This study concerns a new antiretroviral drug named CRS 74. This molecule has a limited bioavailability because of its low aqueous solubility, poor water wettability and low dissolution rate. In an attempt to improve these properties, CRS 74 was recrystallized by using a Liquid Anti-Solvent (LAS) cr...
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| Format: | Others |
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2013
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| Online Access: | http://oatao.univ-toulouse.fr/9301/1/de_paiva_lacerda.pdf |