Identification and validation of small molecules targeting the YTH domain
N6-methyladenosine (m6A) is one of the most common reversible RNA modifications, conserved in all eukaryotes from yeast to humans. It is mainly observed in the 3’UTR, the 5’UTR and near the Transcription Start Sites (TSS), inside a consensus sequence identified as [G/A/U][A/G][m6A-C][U/A/C. The m6A...
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| Format: | Doctoral Thesis |
| Language: | English |
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Università degli studi di Trento
2020
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| Online Access: | http://hdl.handle.net/11572/276926 |