Beyond transcription: p53-dependent cell death response mediated by DHX30

Given its role as “guardian of the genome”, the protein p53 has been extensively studied in the cancer research field, with the aim of exploiting its potential in cancer therapies. Nutlin-3 can be considered the prototype molecule able to activate WT p53 by inhibiting the interaction with its negati...

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Bibliographic Details
Main Author: Rizzotto, Dario
Other Authors: Inga, Alberto
Format: Doctoral Thesis
Language:English
Published: Università degli studi di Trento 2019
Online Access:http://hdl.handle.net/11572/243282

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