Beyond transcription: p53-dependent cell death response mediated by DHX30
Given its role as “guardian of the genome”, the protein p53 has been extensively studied in the cancer research field, with the aim of exploiting its potential in cancer therapies. Nutlin-3 can be considered the prototype molecule able to activate WT p53 by inhibiting the interaction with its negati...
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| Format: | Doctoral Thesis |
| Language: | English |
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Università degli studi di Trento
2019
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| Online Access: | http://hdl.handle.net/11572/243282 |